The published study suggested that cyanobacteria bloom was a phenomenon of excessive reproduction and aggregation with certain nutrient levels, climate and hydrological conditions and was the result of the comprehensive effect of meteorological and water environmental factors such as total nitrogen, total phosphorus, pH values. It was also found that annual outbreak of cyanobacteria bloom in Lake Dianchi indicated that, under the current condition of water quality, the main factor was the meteorological factor. In order to further explore the regularity between meteorological factors and occurrence of cyanobacterial bloom, the relationship between frequency of cyanobacteria bloom and meteorological factors were studied, by using the remote sensing data of cyanobacteria bloom and the monthly meteorological data from the stations nearby Lake Dianchi from 2010 to 2011. The results showed that the cyanobacterial bloom frequency had significant correlation with the average temperature, minimum temperature, average wind speed, cumulative sunshine hours and precipitation, which had a significant negative correlation with sunshine hours and wind speed, respectively. Among the factors, the wind speed had the highest correlation coefficient. It showed that the weaker wind speed was the most closely related to the occurrence of cyanobacteria bloom in Lake Dianchi. And this further verified that the stability of the water body had a more important effect on the occurrence of cyanobacteria bloom, under certain conditions of sufficient nutrients for requires of cyanobacteria bloom. These results can be used as a scientific prediction to forecast the occurrence of cyanobacteria bloom, and to take appropriate measures to reduce the impact of the cyanobacteria bloom.