The ecological forecasting of microorganisms and water quality dynamics in Krasnoyarsk Reservoir is based on knowledge of dependence of specific growth rate (SGR) on limiting substrata. It investigated the influence of soil extract on the growth autochtonic (bacterioplankton of Krasnoyarsk Reservoir. The maximum SGR and Michaelis-Menten constant (on chemical oxidation decomposition (COD)-permanganate) is determined. These parameters are used in eco-model of Krasnoyarsk Reservoir and the Yenisei River to estimate the payojf of self-purification.