Phenotypic plasticity is an ability that an organism activates different phenotypes to its environment. It is an importantsurvival strategy when organisms live in an unstable environment. In aquatic ecosystems, numerous studies prove that planktonicorganisms are able to detect the presence of potential predators through predator-released kairomones, and then evoke someanti-predator responses. Daphnia is a good model of the organism that can be studied for the phenotypic plasticity of zooplanktoninduced by predator-released kairomones. This paper provided an overview of anti-predator phenotypic plasticity of Daphnia inhistorical life traits, morphological characters, behaviors and physiological parameters, and provided the mechanism explanationand ecological significance. These plastic anti-predator changes are shaped by differences in historical exposure to the inducingpredator. Daphnia can inherit these abilities from their parent. Daphnia originated the no-predator ecosystems does not have theability of anti-predator phenotypic plasticity. In general, phenotypic plastic responses of Daphnia induced by predator kairomonescan decrease the efficiency of predation of predators and allow Daphnia a greater chance of survival when facing predators.