It is difficult to fully recognize what the mechanisms are behind Holocene climate changes so far. Numerous geological evidences have suggested that several phases of temperature lowering occurred during the Holocene and the cold phases are correlated with events of volcano explosions. Modern observations in climatology have revealed that volcanic dust plays a role on the radiation blocking and leads to temperature lowering on the earth surface when the volcanic dust enter the stratospheric level. This paper is attempted to focus on both volcanic-climatology and volcanic-geology to understand volcano effects on climate changes, by an integration of geological volcano data and simulation of climate model. The compiling volcanic data show that there were five phases of strong volcanic explosions during 12000-1000 a BP. The volcano-tested climate simulations show that the annual mean temperature is generally decreased during the phase of the strong volcano explosions. Compared to phases of the weak- volcano explosion, the decrease in temperature varied from regions and from seasons. The amplitude of temperature lowering is bigger in high latitude than that in low latitude, and higher in winter than in summer. The results in volcano data set and climate simulations provided the data basis to further study the mechanisms of Holocene climate changes and the today-past analogues to finally predict changes in the future climate in the decade-century scales.