A preliminary study on the advance and retreat of Qingtu Lake, Hexi Corridor and the sedimentary climatic records of Zhiyun Village profile has been made through comprehensive analysis.The study shows that the modes characteristics of climatic change in Eastern Hexi Corridor was provided with the corresponding relationship of warm-moist and cold-dry during the scale longer than hundreds of years.As a result of periodicity of climatic change and human activities, Qingtu Lake cycle has undergone a cycle since 600aBP with four lake-retreat and three lake-advance stages.In brief, the evolution of lakes in Eastern Hexi Corridor is characterized by sedimentary continuity, faster sedimentary rate and higher resolution, which not only can indicate the paleoenvironmental and climatic change in Holocene, but also can reflect the intensity of Eastern Asia monsoon.