Pinqing Lake, which is near Shanwei city, Guangdong Province, is a lagoon. Water flow in the lake is controlled by tide current. As area of Shanwei city expands quickly, more and more urban wastewater pours into the lake. The water quality near an outfall is bad consequently. In this paper, numerical models of 2-D horizontal time-varying flow and diffusion equations are developed. Difference methods are exployed to solve the equations. After increasing domestic and industrial loads are consided, the water quality in Pinqing Lake is predicted by using the mathematics models.