Taihu Lake is one of the famous five great freshwater lakes in China. Taihu Lxike Basin (TLB) is a densely populated and economic developed area in China. The surface water quality in TLB was deteriorated from I-Ⅱ grade in the history to IV-V grade at present. To develop a series of technology of most cost-effective and achievable for improving environment in a local water area of most sensitive for society and improving water quality for more and more areas step by step is the key point of the new strategy. Except the measures for reducing the industrial and domestic pollution load to the lake, some research topics are suggested to be emphasized.